Is Your Idea Worth $4.3 Million Dollars?

The 43 Challenge by the National Pediatric Cancer Foundation is open to new and innovative research proposals.

Grant proposals are valued at $1 million to $4.3 million dollars.

We desire science that can significantly improve the lives of children with cancer, is novel, and makes radical progress against pediatric cancers within the next few years. 

Call for Proposals

New and Innovative Ideas Welcome To Find a Cure For Pediatric Cancer

In recognition of the 43 children a day diagnosed with cancer, the National Pediatric Cancer Foundation (NPCF), is seeking one or more grant proposals valued at $1,000,000 to $4,300,000.

We desire science that can significantly improve the lives of children with cancer, that is novel, innovative, and makes radical progress against pediatric cancers within the next few years.

View our guidelines for more information.

Applications may come from any of the following fields and may be submitted by individuals, multi-disciplinary teams, research institutions, healthcare providers or corporate partnerships by
May 31, 2022:

  • Artificial Intelligence
  • Biology / Ecology
  • Bio-Medical Engineering
  • Medical Physics
  • Molecular Biology
  • Oncology / Biochemistry
  • Therapeutics / Genomics
  • Other

Timeline and Submission Process

  • April 3, 2022

    1

    Applications Open for Letter of Intent

  • May 31, 2022

    2

    Applications Close / Deadline for Letter of Intent Letters

  • June 30, 2022

    3

    Initial NPCF Review and Selection of Projects

  • July 31, 2022

    4

    Full Application Process & Review

  • September 1, 2022

    5

    Announcement of Winner(s)

Submission Process

  • Please completely fill out the Letter of Intent form and attached the requested documents in the form.
    Deadline to Apply: May 31, 2022
    Once an applicant decides on their research project, they submit an LOI / ABSTRACT. This LOI / ABSTRACT is used to check eligibility and to initially interpret proposals to determine which projects will be asked to submit a full proposal.
  • ROUND 1: PROJECTS SHORTLISTED TO SUBMIT FULL APPLICATIONS
    The NPCF Initial Review Committee meet to decide which projects and teams should be selected for submitting full applications. Deadline June 30, 2022.
  • ROUND 2: FULL APPLICATION AND INTERVIEW
    The projects selected submit a full application and will be interviewed by the NPCF / Selection Committee. The selected projects must complete our grant application found here: nationalpcf.org/43challenge. Full application deadline: July 31, 2022.

    For the selected “full application” all nominations must submit the following:
    – The original letter of intent / abstract with any support/additional content
    Bio-sketch. No more than four (4) pages), plus bibliography
    Optional: Two letters of support. Support letters must be written by individuals from institutions outside both the nominators and the nominee’s institution.
    A video (2 minutes or less) that provides an overview / intent / projected outcome of the entry. 

  • ANNOUNCE & AWARD WINNERS: The NPCF Selection Committee will select one or more award winners prior to September 1, 2022, Childhood Cancer Awareness Month.

View our guidelines for more information.

Other Ways to Enter

Prefer a PDF instead of an online form?
Please read our guidelines, and then download our form and submit to: 43Challenge@NationalPCF.org

Make sure to include the following attachments in your email:

  1. The 43 Challenge Submission Form completely filled out.
  2. A basic budget within $10,000 with supplies and personnel estimates (15% indirect cap).
  3. The Bio-Sketch / Bibliography of the PI.

Letter of Intent Form

Please fill out the form completely. When submitting form, please include requested attachments: This form, a basic budget within $10,000 with supplies and personnel estimates (15% indirect cap), and a bio-sketch / bibliography of PI. Failure to complete this form in its entirety can result in a delay or incompletion of your submission. Thank you and best of luck on your grant proposal submission.

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